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Selectivity of Enzymatic Conversion of Oligonucleotide Probes during Nucleotide Polymorphism Analysis of DNA

The analysis of DNA nucleotide polymorphisms is one of the main goals of DNA diagnostics. DNA–dependent enzymes (DNA polymerases and DNA ligases) are widely used to enhance the sensitivity and reliability of systems intended for the detection of point mutations in genetic material. In this article,...

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Main Authors: Vinogradova, O.A., Pyshnyi, D.V.
Format: Artigo
Sprog:Inglês
Udgivet: A.I. Gordeyev 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347538/
https://ncbi.nlm.nih.gov/pubmed/22649627
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