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Evaluating oligonucleotide properties for DNA microarray probe design

Most current microarray oligonucleotide probe design strategies are based on probe design factors (PDFs), which include probe hybridization free energy (PHFE), probe minimum folding energy (PMFE), dimer score, hairpin score, homology score and complexity score. The impact of these PDFs on probe perf...

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Detalhes bibliográficos
Main Authors: Xia, Xiao-Qin, Jia, Zhenyu, Porwollik, Steffen, Long, Fred, Hoemme, Claudia, Ye, Kai, Müller-Tidow, Carsten, McClelland, Michael, Wang, Yipeng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887943/
https://ncbi.nlm.nih.gov/pubmed/20236987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq039
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