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Sensing Enzymatic Activity by Exposure and Selection of DNA-encoded Probes

A sensing approach is described and is applied to encode quantitative enzymatic activity information into DNA sequence populations. The method utilizes DNA-linked peptide substrates as activity probes. Signal detection involves chemical manipulation of a probe population downstream of sample exposur...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Angew Chem Int Ed Engl
Prif Awduron: Jetson, Rachael R., Krusemark, Casey J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402352/
https://ncbi.nlm.nih.gov/pubmed/27355201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603387
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