Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile

Smad2 and Smad3 are closely related effectors of TGFβ/Nodal/Activin-related signaling. Smad3 mutant mice develop normally, whereas Smad2 plays an essential role in patterning the embryonic axis and specification of definitive endoderm. Alternative splicing of Smad2 exon 3 gives rise to two distinct...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Dunn, N. Ray, Koonce, Chad H., Anderson, Dorian C., Islam, Ayesha, Bikoff, Elizabeth K., Robertson, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC540233/
https://ncbi.nlm.nih.gov/pubmed/15630024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1243205
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares