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Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo

Three closely related mammalian R-Smads, namely Smad1, Smad5 and Smad8, are activated by BMP receptors. Here we have taken a genetic approach to further dissect their possibly unique and/or shared roles during early mouse development. A Smad8.LacZ reporter allele was created to visualize Smad8 expre...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Arnold, Sebastian J., Maretto, Silvia, Islam, Ayesha, Bikoff, Elizabeth K., Robertson, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116376/
https://ncbi.nlm.nih.gov/pubmed/16765933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.04.442
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