Fluid shear stress induces upregulation of COX-2 and PGI(2) release in endothelial cells via a pathway involving PECAM-1, PI3K, FAK, and p38

Vascular endothelial cells play an important role in the regulation of vascular function in response to mechanical stimuli in both healthy and diseased states. Prostaglandin I(2) (PGI(2)) is an important antiatherogenic prostanoid and vasodilator produced in endothelial cells through the action of t...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Heart Circ Physiol
Hoofdauteurs: Russell-Puleri, Sparkle, dela Paz, Nathaniel G., Adams, Diana, Chattopadhyay, Mitali, Cancel, Limary, Ebong, Eno, Orr, A. Wayne, Frangos, John A., Tarbell, John M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402016/
https://ncbi.nlm.nih.gov/pubmed/28011582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00035.2016
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