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Heparan sulfate proteoglycan glypican-1 and PECAM-1 cooperate in shear-induced endothelial nitric oxide production

This study aimed to clarify the role of glypican-1 and PECAM-1 in shear-induced nitric oxide production in endothelial cells. Atomic force microscopy pulling was used to apply force to glypican-1 and PECAM-1 on the surface of human umbilical vein endothelial cells and nitric oxide was measured using...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bartosch, Anne Marie W., Mathews, Rick, Mahmoud, Marwa M., Cancel, Limary M., Haq, Zahin S., Tarbell, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166914/
https://ncbi.nlm.nih.gov/pubmed/34059731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90941-w
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