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Enabling the controlled assembly of antibody conjugates with a loading of two modules without antibody engineering

The generation of antibody conjugates with a loading of two modules is desirable for a host of reasons. Whilst certain antibody engineering approaches have been useful in the preparation of such constructs, a reliable method based on a native antibody scaffold without the use of enzymes or harsh oxi...

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書目詳細資料
發表在:Chem Sci
Main Authors: Lee, Maximillian T. W., Maruani, Antoine, Richards, Daniel A., Baker, James R., Caddick, Stephen, Chudasama, Vijay
格式: Artigo
語言:Inglês
出版: Royal Society of Chemistry 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399535/
https://ncbi.nlm.nih.gov/pubmed/28451324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc03655d
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