Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma

Dysregulated oncogenic serine/threonine kinases play a pathological role in diverse forms of malignancies, including multiple myeloma (MM), and thus represent potential therapeutic targets. Here, we evaluated the biological and functional role of p21-activated kinase 4 (PAK4) and its potential as a...

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Pubblicato in:Blood
Autori principali: Fulciniti, Mariateresa, Martinez-Lopez, Joaquin, Senapedis, William, Oliva, Stefania, Lakshmi Bandi, Rajya, Amodio, Nicola, Xu, Yan, Szalat, Raphael, Gulla, Annamaria, Samur, Mehmet K., Roccaro, Aldo, Linares, Maria, Cea, Michele, Baloglu, Erkan, Argueta, Christian, Landesman, Yosef, Shacham, Sharon, Liu, Siyuan, Schenone, Monica, Wu, Shiaw-Lin, Karger, Barry, Prabhala, Rao, Anderson, Kenneth C., Munshi, Nikhil C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2017
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399480/
https://ncbi.nlm.nih.gov/pubmed/28096095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-724831
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