MYD88-independent growth and survival effects of Sp1 transactivation in Waldenström macroglobulinemia

Sp1 transcription factor controls a pleiotropic group of genes and its aberrant activation has been reported in a number of malignancies, including multiple myeloma. In this study, we investigate and report its aberrant activation in Waldenström macroglobulinemia (WM). Both loss of and gain of Sp1 f...

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Hlavní autoři: Fulciniti, Mariateresa, Amodio, Nicola, Bandi, Rajya Lakshmi, Munshi, Mansa, Yang, Guang, Xu, Lian, Hunter, Zachary, Tassone, Pierfrancesco, Anderson, Kenneth C., Treon, Steven P., Munshi, Nikhil C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2014
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999753/
https://ncbi.nlm.nih.gov/pubmed/24622324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-550509
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