The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2

We examined whether the scaffolding protein sodium-hydrogen exchanger regulatory factor 1 (NHERF1) interacts with the calcium pump PMCA2 and the tyrosine kinase receptor ErbB2/HER2 in normal mammary epithelial cells and breast cancer cells. NHERF1 interacts with the PDZ-binding motif in PMCA2 in bot...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Jeong, Jaekwang, VanHouten, Joshua N., Kim, Wonnam, Dann, Pamela, Sullivan, Catherine, Choi, Jungmin, Sneddon, W. Bruce, Friedman, Peter A., Wysolmerski, John J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2017
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399107/
https://ncbi.nlm.nih.gov/pubmed/28235801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770883
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