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Calcium-Sensing Receptor (CaSR) Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone-Related Protein

Parathyroid hormone-related protein (PTHrP) contributes to the development and metastatic progression of breast cancer by promoting hypercalcemia, tumor growth and osteolytic bone metastases, but it is not known how PTHrP is upregulated in breast tumors. Here we report a central role in this process...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Kim, Wonnam, Takyar, Farzin M., Swan, Karena, Jeong, Jaekwang, VanHouten, Joshua, Sullivan, Catherine, Dann, Pamela, Yu, Herbert, Fiaschi-Taesch, Nathalie, Chang, Wenhan, Wysolmerski, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026591/
https://ncbi.nlm.nih.gov/pubmed/27450451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2614
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