Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats

Estrogens play a crucial role in the causation and development of sporadic human breast cancer (BC). Chromosomal instability (CIN) is a defining trait of early human ductal carcinoma in situ (DCIS) and is believed to precipitate breast oncogenesis. We reported earlier that 100% of female ACI (August...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Li, Jonathan J., Weroha, S. John, Lingle, Wilma L., Papa, Dan, Salisbury, Jeffrey L., Li, Sara Antonia
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC539804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15601761/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408273101
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