Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats

Estrogens play a crucial role in the causation and development of sporadic human breast cancer (BC). Chromosomal instability (CIN) is a defining trait of early human ductal carcinoma in situ (DCIS) and is believed to precipitate breast oncogenesis. We reported earlier that 100% of female ACI (August...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Jonathan J., Weroha, S. John, Lingle, Wilma L., Papa, Dan, Salisbury, Jeffrey L., Li, Sara Antonia
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2004
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC539804/
https://ncbi.nlm.nih.gov/pubmed/15601761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408273101
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