Epstein–Barr virus particles induce centrosome amplification and chromosomal instability

Infections with Epstein–Barr virus (EBV) are associated with cancer development, and EBV lytic replication (the process that generates virus progeny) is a strong risk factor for some cancer types. Here we report that EBV infection of B-lymphocytes (in vitro and in a mouse model) leads to an increase...

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Publicat a:Nat Commun
Autors principals: Shumilov, Anatoliy, Tsai, Ming-Han, Schlosser, Yvonne T., Kratz, Anne-Sophie, Bernhardt, Katharina, Fink, Susanne, Mizani, Tuba, Lin, Xiaochen, Jauch, Anna, Mautner, Josef, Kopp-Schneider, Annette, Feederle, Regina, Hoffmann, Ingrid, Delecluse, Henri-Jacques
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309802/
https://ncbi.nlm.nih.gov/pubmed/28186092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14257
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