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Epstein-Barr Viruses That Express a CD21 Antibody Provide Evidence that gp350's Functions Extend beyond B-Cell Surface Binding

The gp350 glycoprotein encoded by BLLF1 is crucial for efficient Epstein-Barr virus (EBV) infection of resting B cells. Gp350 binds to CD21, but whether this interaction sums up its functions remains unknown. We generated gp350-null EBVs that display CD19-, CD21-, or CD22-specific antibodies at thei...

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Detalhes bibliográficos
Main Authors: Busse, Clemens, Feederle, Regina, Schnölzer, Martina, Behrends, Uta, Mautner, Josef, Delecluse, Henri-Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798361/
https://ncbi.nlm.nih.gov/pubmed/19889766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01953-09
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