Centrosome amplification drives chromosomal instability in breast tumor development

Earlier studies of invasive breast tumors have shown that 60–80% are aneuploid and ≈80% exhibit amplified centrosomes. In this study, we investigated the relationship of centrosome amplification with aneuploidy, chromosomal instability, p53 mutation, and loss of differentiation in human breast tumor...

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Detaylı Bibliyografya
Asıl Yazarlar: Lingle, Wilma L., Barrett, Susan L., Negron, Vivian C., D'Assoro, Antonino B., Boeneman, Kelly, Liu, Wanguo, Whitehead, Clark M., Reynolds, Carol, Salisbury, Jeffrey L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2002
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC122305/
https://ncbi.nlm.nih.gov/pubmed/11830638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032479999
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