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Centrosome amplification drives chromosomal instability in breast tumor development
Earlier studies of invasive breast tumors have shown that 60–80% are aneuploid and ≈80% exhibit amplified centrosomes. In this study, we investigated the relationship of centrosome amplification with aneuploidy, chromosomal instability, p53 mutation, and loss of differentiation in human breast tumor...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The National Academy of Sciences
2002
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122305/ https://ncbi.nlm.nih.gov/pubmed/11830638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032479999 |
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