Chargement en cours...

CrkII regulates focal adhesion kinase activation by making a complex with Crk-associated substrate, p130(Cas)

CrkII is an adaptor protein possessing oncogenic potential despite the lack of an enzymatic domain. We investigated here the physiological functions of CrkII by studying its ability to induce anchorage-independent cell growth. We found that inhibition or null mutation of focal adhesion kinase (FAK)...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Iwahara, Toshinori, Akagi, Tsuyoshi, Fujitsuka, Yuki, Hanafusa, Hidesaburo
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC539787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15598735/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408413102
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!