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Identification of Novel Crk-associated Substrate (p130(Cas)) Variants with Functionally Distinct Focal Adhesion Kinase Binding Activities
Elevated levels of p130(Cas) (Crk-associated substrate)/BCAR1 (breast cancer antiestrogen resistance 1 gene) are associated with aggressiveness of breast tumors. Following phosphorylation of its substrate domain, p130(Cas) promotes the integration of protein complexes involved in multiple signaling...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4424356/ https://ncbi.nlm.nih.gov/pubmed/25805500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649947 |
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