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Comprehensive evaluation of genome-wide 5-hydroxymethylcytosine profiling approaches in human DNA
BACKGROUND: The discovery that 5-methylcytosine (5mC) can be oxidized to 5-hydroxymethylcytosine (5hmC) by the ten-eleven translocation (TET) proteins has prompted wide interest in the potential role of 5hmC in reshaping the mammalian DNA methylation landscape. The gold-standard bisulphite conversio...
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| Publicado en: | Epigenetics Chromatin |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5397694/ https://ncbi.nlm.nih.gov/pubmed/28428825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-017-0123-7 |
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