Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer

DNA replication timing is known to facilitate the establishment of the epigenome, however, the intimate connection between replication timing and changes to the genome and epigenome in cancer remain largely uncharacterised. Here, we perform Repli-Seq and integrated epigenome analyses and demonstrate...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Du, Qian, Bert, Saul A., Armstrong, Nicola J., Caldon, C. Elizabeth, Song, Jenny Z., Nair, Shalima S., Gould, Cathryn M., Luu, Phuc-Loi, Peters, Timothy, Khoury, Amanda, Qu, Wenjia, Zotenko, Elena, Stirzaker, Clare, Clark, Susan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345877/
https://ncbi.nlm.nih.gov/pubmed/30679435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08302-1
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