Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

BACKGROUND: In recent years the Illumina HumanMethylation450 (HM450) BeadChip has provided a user-friendly platform to profile DNA methylation in human samples. However, HM450 lacked coverage of distal regulatory elements. Illumina have now released the MethylationEPIC (EPIC) BeadChip, with new cont...

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Publicado en:Genome Biol
Autores principales: Pidsley, Ruth, Zotenko, Elena, Peters, Timothy J., Lawrence, Mitchell G., Risbridger, Gail P., Molloy, Peter, Van Djik, Susan, Muhlhausler, Beverly, Stirzaker, Clare, Clark, Susan J.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055731/
https://ncbi.nlm.nih.gov/pubmed/27717381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1066-1
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