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Distinguishing Active Versus Passive DNA Demethylation Using Illumina MethylationEPIC BeadChip Microarrays

The 5-carbon positions on cytosine nucleotides preceding guanines in genomic DNA (CpG) are common targets for DNA methylation (5mC). DNA methylation removal can occur through both active and passive mechanisms. Ten-eleven translocation enzymes (TETs) oxidize 5mC in a stepwise manner to 5-hydroxymeth...

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Udgivet i:Methods Mol Biol
Main Authors: Tiedemann, Rochelle L., Eden, Hope E., Huang, Zhijun, Robertson, Keith D., Rothbart, Scott B.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265207/
https://ncbi.nlm.nih.gov/pubmed/34009611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-1294-1_7
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