Evaluation of affinity-based genome-wide DNA methylation data: Effects of CpG density, amplification bias, and copy number variation

DNA methylation is an essential epigenetic modification that plays a key role associated with the regulation of gene expression during differentiation, but in disease states such as cancer, the DNA methylation landscape is often deregulated. There are now numerous technologies available to interroga...

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Detalhes bibliográficos
Main Authors: Robinson, Mark D., Stirzaker, Clare, Statham, Aaron L., Coolen, Marcel W., Song, Jenny Z., Nair, Shalima S., Strbenac, Dario, Speed, Terence P., Clark, Susan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989998/
https://ncbi.nlm.nih.gov/pubmed/21045081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.110601.110
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