Targeting the Mitochondrial Pyruvate Carrier Attenuates Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis

Diseases of the liver related to metabolic syndrome have emerged as the most common and undertreated hepatic ailments. The cause of nonalcoholic fatty liver disease (NAFLD) is the aberrant accumulation of lipid in hepatocytes, though the mechanisms whereby this leads to hepatocyte dysfunction, death...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hepatology
Prif Awduron: McCommis, Kyle S., Hodges, Wesley T., Brunt, Elizabeth M., Nalbantoglu, ILKe, McDonald, William G., Holley, Christopher, Fujiwara, Hideji, Schaffer, Jean E., Colca, Jerry R., Finck, Brian N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397348/
https://ncbi.nlm.nih.gov/pubmed/28027586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29025
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