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Targeting the Mitochondrial Pyruvate Carrier Attenuates Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis

Diseases of the liver related to metabolic syndrome have emerged as the most common and undertreated hepatic ailments. The cause of nonalcoholic fatty liver disease (NAFLD) is the aberrant accumulation of lipid in hepatocytes, though the mechanisms whereby this leads to hepatocyte dysfunction, death...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: McCommis, Kyle S., Hodges, Wesley T., Brunt, Elizabeth M., Nalbantoglu, ILKe, McDonald, William G., Holley, Christopher, Fujiwara, Hideji, Schaffer, Jean E., Colca, Jerry R., Finck, Brian N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397348/
https://ncbi.nlm.nih.gov/pubmed/28027586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29025
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