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An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion
OBJECTIVE: Transport of pyruvate into the mitochondrial matrix by the Mitochondrial Pyruvate Carrier (MPC) is an important and rate-limiting step in its metabolism. In pancreatic β-cells, mitochondrial pyruvate metabolism is thought to be important for glucose sensing and glucose-stimulated insulin...
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| 出版年: | Mol Metab |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021712/ https://ncbi.nlm.nih.gov/pubmed/27656398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.06.016 |
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