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Treating fatty liver disease by modulating mitochondrial pyruvate metabolism

Modifying the entry of pyruvate into mitochondria may provide a unique approach to treat metabolic disease. The pharmacology of a new class of insulin sensitizers directed against a newly identified mitochondrial target may treat many aspects of nonalcoholic steatohepatitis, including fibrosis. This...

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Bibliografische gegevens
Gepubliceerd in:Hepatol Commun
Hoofdauteurs: Colca, Jerry R., McDonald, William G., McCommis, Kyle S., Finck, Brian N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721453/
https://ncbi.nlm.nih.gov/pubmed/29404453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1036
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