An Insulin-Sensitizing Thiazolidinedione, Which Minimally Activates PPARγ, Does Not Cause Bone Loss

অনুযায়ী Fukunaga, Tomohiro, Zou, Wei, Rohatgi, Nidhi, Colca, Jerry R., Teitelbaum, Steven L.
প্রকাশিত J Bone Miner Res (2015)

Treating fatty liver disease by modulating mitochondrial pyruvate metabolism

অনুযায়ী Colca, Jerry R., McDonald, William G., McCommis, Kyle S., Finck, Brian N.
প্রকাশিত Hepatol Commun (2017)

Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide

অনুযায়ী Kamm, Dakota R., Pyles, Kelly D., Sharpe, Martin C., Healy, Laura N., Colca, Jerry R., McCommis, Kyle S.
প্রকাশিত J Biol Chem (2021)

Novel Insulin Sensitizer Modulates Nutrient Sensing Pathways and Maintains β-Cell Phenotype in Human Islets

অনুযায়ী Rohatgi, Nidhi, Aly, Haytham, Marshall, Connie A., McDonald, William G., Kletzien, Rolf F., Colca, Jerry R., McDaniel, Michael L.
প্রকাশিত 2013

An Evaluation of MSDC-0160, A Prototype mTOT Modulating Insulin Sensitizer, in Patients with Mild Alzheimer’s Disease

অনুযায়ী Shah, Raj C, Matthews, Dawn C, Andrews, Randolph D, Capuano, Ana W, Fleischman, Debra A, VanderLugt, James T, Colca, Jerry R
প্রকাশিত 2014

Loss of Mitochondrial Pyruvate Carrier 2 in Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling

অনুযায়ী McCommis, Kyle S., Chen, Zhouji, Fu, Xiaorong, McDonald, William G., Colca, Jerry R., Kletzien, Rolf F., Burgess, Shawn C., Finck, Brian N.
প্রকাশিত Cell Metab (2015)

Insulin Resistance and Metabolic Derangements in Obese Mice Are Ameliorated by a Novel Peroxisome Proliferator-activated Receptor γ-sparing Thiazolidinedione

অনুযায়ী Chen, Zhouji, Vigueira, Patrick A., Chambers, Kari T., Hall, Angela M., Mitra, Mayurranjan S., Qi, Nathan, McDonald, William G., Colca, Jerry R., Kletzien, Rolf F., Finck, Brian N.
প্রকাশিত 2012

Targeting the Mitochondrial Pyruvate Carrier Attenuates Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis

অনুযায়ী McCommis, Kyle S., Hodges, Wesley T., Brunt, Elizabeth M., Nalbantoglu, ILKe, McDonald, William G., Holley, Christopher, Fujiwara, Hideji, Schaffer, Jean E., Colca, Jerry R., Finck, Brian N.
প্রকাশিত Hepatology (2017)

The Beneficial Metabolic Effects of Insulin Sensitizers are not Attenuated by Mitochondrial Pyruvate Carrier 2 Hypomorphism

অনুযায়ী Vigueira, Patrick A., McCommis, Kyle S., Hodges, Wesley T., Schweitzer, George G., Cole, Serena L., Oonthonpan, Lalita, Taylor, Eric B., McDonald, William G., Kletzien, Rolf F., Colca, Jerry R., Finck, Brian N.
প্রকাশিত Exp Physiol (2017)

Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion

অনুযায়ী Vigueira, Patrick A., McCommis, Kyle S., Schweitzer, George G., Remedi, Maria S., Chambers, Kari T., Fu, Xiaorong, McDonald, William G., Cole, Serena L., Colca, Jerry R., Kletzien, Rolf F., Burgess, Shawn C., Finck, Brian N.
প্রকাশিত 2014

Insulin Sensitizing Pharmacology of Thiazolidinediones Correlates with Mitochondrial Gene Expression rather than Activation of PPARγ

অনুযায়ী Bolten, Charles W., Blanner, Patrick M., McDonald, William G., Staten, Nicholas R., Mazzarella, Richard A., Arhancet, Graciela B., Meier, Martin F., Weiss, David J., Sullivan, Patrick M., Hromockyj, Alexander E., Kletzien, Rolf F., Colca, Jerry R.
প্রকাশিত 2007

Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier

অনুযায়ী Divakaruni, Ajit S., Wiley, Sandra E., Rogers, George W., Andreyev, Alexander Y., Petrosyan, Susanna, Loviscach, Mattias, Wall, Estelle A., Yadava, Nagendra, Heuck, Alejandro P., Ferrick, David A., Henry, Robert R., McDonald, William G., Colca, Jerry R., Simon, Melvin I., Ciaraldi, Theodore P., Murphy, Anne N.
প্রকাশিত 2013

Identification of a Mitochondrial Target of Thiazolidinedione Insulin Sensitizers (mTOT)—Relationship to Newly Identified Mitochondrial Pyruvate Carrier Proteins

অনুযায়ী Colca, Jerry R., McDonald, William G., Cavey, Gregory S., Cole, Serena L., Holewa, Danielle D., Brightwell-Conrad, Angela S., Wolfe, Cindy L., Wheeler, Jean S., Coulter, Kristin R., Kilkuskie, Peter M., Gracheva, Elena, Korshunova, Yulia, Trusgnich, Michelle, Karr, Robert, Wiley, Sandra E., Divakaruni, Ajit S., Murphy, Anne N., Vigueira, Patrick A., Finck, Brian N., Kletzien, Rolf F.
প্রকাশিত 2013