Identification of a Mitochondrial Target of Thiazolidinedione Insulin Sensitizers (mTOT)—Relationship to Newly Identified Mitochondrial Pyruvate Carrier Proteins

Thiazolidinedione (TZD) insulin sensitizers have the potential to effectively treat a number of human diseases, however the currently available agents have dose-limiting side effects that are mediated via activation of the transcription factor PPARγ. We have recently shown PPARγ-independent actions...

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Bibliografski detalji
Glavni autori: Colca, Jerry R., McDonald, William G., Cavey, Gregory S., Cole, Serena L., Holewa, Danielle D., Brightwell-Conrad, Angela S., Wolfe, Cindy L., Wheeler, Jean S., Coulter, Kristin R., Kilkuskie, Peter M., Gracheva, Elena, Korshunova, Yulia, Trusgnich, Michelle, Karr, Robert, Wiley, Sandra E., Divakaruni, Ajit S., Murphy, Anne N., Vigueira, Patrick A., Finck, Brian N., Kletzien, Rolf F.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655167/
https://ncbi.nlm.nih.gov/pubmed/23690925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061551
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