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Treating fatty liver disease by modulating mitochondrial pyruvate metabolism
Modifying the entry of pyruvate into mitochondria may provide a unique approach to treat metabolic disease. The pharmacology of a new class of insulin sensitizers directed against a newly identified mitochondrial target may treat many aspects of nonalcoholic steatohepatitis, including fibrosis. This...
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| Veröffentlicht in: | Hepatol Commun |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5721453/ https://ncbi.nlm.nih.gov/pubmed/29404453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1036 |
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