Editing of misaminoacylated tRNA controls the sensitivity of amino acid stress responses in Saccharomyces cerevisiae

Amino acid starvation activates the protein kinase Gcn2p, leading to changes in gene expression and translation. Gcn2p is activated by deacylated tRNA, which accumulates when tRNA aminoacylation is limited by lack of substrates or inhibition of synthesis. Pairing of amino acids and deacylated tRNAs...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Mohler, Kyle, Mann, Rebecca, Bullwinkle, Tammy J., Hopkins, Kyle, Hwang, Lin, Reynolds, Noah M., Gassaway, Brandon, Aerni, Hans-Rudolf, Rinehart, Jesse, Polymenis, Michael, Faull, Kym, Ibba, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
Assuntos:
Nucleic Acid Enzymes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397148/
https://ncbi.nlm.nih.gov/pubmed/28168297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx077
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