Editing of misaminoacylated tRNA controls the sensitivity of amino acid stress responses in Saccharomyces cerevisiae

Amino acid starvation activates the protein kinase Gcn2p, leading to changes in gene expression and translation. Gcn2p is activated by deacylated tRNA, which accumulates when tRNA aminoacylation is limited by lack of substrates or inhibition of synthesis. Pairing of amino acids and deacylated tRNAs...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Mohler, Kyle, Mann, Rebecca, Bullwinkle, Tammy J., Hopkins, Kyle, Hwang, Lin, Reynolds, Noah M., Gassaway, Brandon, Aerni, Hans-Rudolf, Rinehart, Jesse, Polymenis, Michael, Faull, Kym, Ibba, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397148/
https://ncbi.nlm.nih.gov/pubmed/28168297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx077
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