Editing of misaminoacylated tRNA controls the sensitivity of amino acid stress responses in Saccharomyces cerevisiae

Amino acid starvation activates the protein kinase Gcn2p, leading to changes in gene expression and translation. Gcn2p is activated by deacylated tRNA, which accumulates when tRNA aminoacylation is limited by lack of substrates or inhibition of synthesis. Pairing of amino acids and deacylated tRNAs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Mohler, Kyle, Mann, Rebecca, Bullwinkle, Tammy J., Hopkins, Kyle, Hwang, Lin, Reynolds, Noah M., Gassaway, Brandon, Aerni, Hans-Rudolf, Rinehart, Jesse, Polymenis, Michael, Faull, Kym, Ibba, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Nucleic Acid Enzymes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397148/
https://ncbi.nlm.nih.gov/pubmed/28168297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx077
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