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Control of Transcriptional Fidelity by Active Center Tuning as Derived from RNA Polymerase Endonuclease Reaction
Precise transcription by cellular RNA polymerase requires the efficient removal of noncognate nucleotide residues that are occasionally incorporated. Mis-incorporation causes the transcription elongation complex to backtrack, releasing a single strand 3′-RNA segment bearing a noncognate residue, whi...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5396497/ https://ncbi.nlm.nih.gov/pubmed/23283976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424002 |
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