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Synthetic lethality: emerging targets and opportunities in melanoma
Great progress has been made in the treatment of melanoma through use of targeted therapies and immunotherapy. One approach that has not been fully explored is synthetic lethality, which exploits somatically acquired changes, usually driver mutations, to specifically kill tumour cells. We outline th...
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| Published in: | Pigment Cell Melanoma Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5396340/ https://ncbi.nlm.nih.gov/pubmed/28097822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12573 |
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