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α-Synuclein’s uniquely long amphipathic helix enhances its membrane binding and remodeling capacity
α-Synuclein is the primary protein found in Lewy bodies, the protein and lipid aggregates associated with Parkinson’s disease and Lewy body dementia. The protein folds into a uniquely long amphipathic α-helix (AH) when bound to a membrane, and at high enough concentrations induces large scale remode...
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| Publicado no: | J Membr Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5394797/ https://ncbi.nlm.nih.gov/pubmed/28239748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-017-9946-1 |
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