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Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein

We review experimental and simulation approaches that have been used to determine curvature generation and remodeling of lipid bilayers by membrane-bending proteins. Particular emphasis is placed on the complementary approaches used to study α-Synuclein (αSyn), a major protein involved in Parkinson&...

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Publicat a:Biochim Biophys Acta
Autors principals: West, Ana, Brummel, Benjamin E., Braun, Anthony R., Rhoades, Elizabeth, Sachs, Jonathan N.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081225/
https://ncbi.nlm.nih.gov/pubmed/26972046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2016.03.012
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