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Polyunsaturated chains in asymmetric lipids disorder raft mixtures and preferentially associate with α-Synuclein

Using molecular dynamics simulations, we have explored the effect of asymmetric lipids—specifically those that contain one polyunsaturated (PUFA) and one saturated fatty acid chain—on phase separation in heterogeneous membranes. These lipids are prevalent in neuronal membranes, particularly in synap...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta
Main Authors: Brummel, Benjamin E., Braun, Anthony R., Sachs, Jonathan N.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749632/
https://ncbi.nlm.nih.gov/pubmed/27742354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2016.10.006
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