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Biophysics of α-synuclein induced membrane remodelling

α-synuclein is an intrinsically disordered protein whose aggregation is a hallmark of Parkinson’s disease. In neurons, α-synuclein is thought to play important roles in mediating both endo- and exocytosis of synaptic vesicles through interactions with either the lipid bilayer or other proteins. Upon...

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Pubblicato in:Phys Chem Chem Phys
Autori principali: Shi, Zheng, Sachs, Jonathan, Rhoades, Elizabeth, Baumgart, Tobias
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464955/
https://ncbi.nlm.nih.gov/pubmed/25665896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cp05883f
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