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α-Synuclein’s uniquely long amphipathic helix enhances its membrane binding and remodeling capacity

α-Synuclein is the primary protein found in Lewy bodies, the protein and lipid aggregates associated with Parkinson’s disease and Lewy body dementia. The protein folds into a uniquely long amphipathic α-helix (AH) when bound to a membrane, and at high enough concentrations induces large scale remode...

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Detaylı Bibliyografya
Yayımlandı:J Membr Biol
Asıl Yazarlar: Braun, Anthony R., Lacy, Michael M., Ducas, Vanessa C., Rhoades, Elizabeth, Sachs, Jonathan N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394797/
https://ncbi.nlm.nih.gov/pubmed/28239748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-017-9946-1
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