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Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer

Allosteric modulators that are targeting the calcium-sensing receptor (CaSR) hold great therapeutic potential, and elucidating the molecular basis for modulation would thus benefit the development of novel therapeutics. In the present study, we aimed at investigating the mechanism of allosteric modu...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Jacobsen, Stine Engesgaard, Gether, Ulrik, Bräuner-Osborne, Hans
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394417/
https://ncbi.nlm.nih.gov/pubmed/28417952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46355
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