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Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer
Allosteric modulators that are targeting the calcium-sensing receptor (CaSR) hold great therapeutic potential, and elucidating the molecular basis for modulation would thus benefit the development of novel therapeutics. In the present study, we aimed at investigating the mechanism of allosteric modu...
Gespeichert in:
| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5394417/ https://ncbi.nlm.nih.gov/pubmed/28417952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46355 |
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