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Allosteric Modulation of the Calcium-Sensing Receptor

The calcium (Ca(2+))-sensing receptor (CaR) belongs to family C of the G-protein coupled receptors (GPCRs). The receptor is activated by physiological levels of Ca(2+) (and Mg(2+)) and positively modulated by a range of proteinogenic L-α-amino acids. Recently, several synthetic allosteric modulators...

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Autori principali: Jensen, Anders A, Bräuner-Osborne, Hans
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bentham Science Publishers Ltd. 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656812/
https://ncbi.nlm.nih.gov/pubmed/19305800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157015907781695982
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