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Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose

The calcium-sensing receptor (CaSR) is activated by various cations, cationic compounds, and amino acids. In the present study we investigated the effect of glucose on CaSR in HEK293 cells stably expressing human CaSR (HEK-CaSR cells). When glucose concentration in the buffer was raised from 3 to 25...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Medina, Johan, Nakagawa, Yuko, Nagasawa, Masahiro, Fernandez, Anny, Sakaguchi, Kazushige, Kitaguchi, Tetsuya, Kojima, Itaru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087731/
https://ncbi.nlm.nih.gov/pubmed/27613866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729863
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