Return of the glucoreceptor: Glucose activates the glucose-sensing receptor T1R3 and facilitates metabolism in pancreatic β-cells

Subunits of the sweet taste receptor, namely T1R2 and T1R3, are expressed in mouse pancreatic islets. Quantitatively, the expression of messenger ribonucleic acid for T1R2 is much lower than that of T1R3, and immunoreactive T1R2 is in fact undetectable. Presumably, a homodimer of T1R3 could function...

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Bibliographic Details
Published in:J Diabetes Investig
Main Authors: Kojima, Itaru, Nakagawa, Yuko, Ohtsu, Yoshiaki, Hamano, Kunihisa, Medina, Johan, Nagasawa, Masahiro
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2015
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420555/
https://ncbi.nlm.nih.gov/pubmed/25969708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12304
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