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Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose

The calcium-sensing receptor (CaSR) is activated by various cations, cationic compounds, and amino acids. In the present study we investigated the effect of glucose on CaSR in HEK293 cells stably expressing human CaSR (HEK-CaSR cells). When glucose concentration in the buffer was raised from 3 to 25...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Medina, Johan, Nakagawa, Yuko, Nagasawa, Masahiro, Fernandez, Anny, Sakaguchi, Kazushige, Kitaguchi, Tetsuya, Kojima, Itaru
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087731/
https://ncbi.nlm.nih.gov/pubmed/27613866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729863
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