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Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose

The calcium-sensing receptor (CaSR) is activated by various cations, cationic compounds, and amino acids. In the present study we investigated the effect of glucose on CaSR in HEK293 cells stably expressing human CaSR (HEK-CaSR cells). When glucose concentration in the buffer was raised from 3 to 25...

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Publicado en:J Biol Chem
Main Authors: Medina, Johan, Nakagawa, Yuko, Nagasawa, Masahiro, Fernandez, Anny, Sakaguchi, Kazushige, Kitaguchi, Tetsuya, Kojima, Itaru
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087731/
https://ncbi.nlm.nih.gov/pubmed/27613866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729863
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