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Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose

The calcium-sensing receptor (CaSR) is activated by various cations, cationic compounds, and amino acids. In the present study we investigated the effect of glucose on CaSR in HEK293 cells stably expressing human CaSR (HEK-CaSR cells). When glucose concentration in the buffer was raised from 3 to 25...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Medina, Johan, Nakagawa, Yuko, Nagasawa, Masahiro, Fernandez, Anny, Sakaguchi, Kazushige, Kitaguchi, Tetsuya, Kojima, Itaru
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2016
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087731/
https://ncbi.nlm.nih.gov/pubmed/27613866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729863
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