Laddar...
Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease
Recessive Stargardt macular degeneration (STGD1) is caused by mutations in the gene for the ABCA4 transporter in photoreceptor outer segments. STGD1 patients and Abca4(−/−) (STGD1) mice exhibit buildup of bisretinoid-containing lipofuscin pigments in the retinal pigment epithelium (RPE), increased o...
Sparad:
| I publikationen: | Proc Natl Acad Sci U S A |
|---|---|
| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2017
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5393232/ https://ncbi.nlm.nih.gov/pubmed/28348233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620299114 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|