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Photoreceptor degeneration in microphthalmia (Mitf) mice: partial rescue by pigment epithelium-derived factor

Dysfunction and loss of the retinal pigment epithelium (RPE) are hallmarks of retinal degeneration, but the underlying pathogenetic processes are only partially understood. Using mice with a null mutation in the transcription factor gene Mitf, in which RPE deficiencies are associated with retinal de...

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Enregistré dans:
Détails bibliographiques
Publié dans:Dis Model Mech
Auteurs principaux: Chen, Yu, Yang, Juan, Geng, Huiqin, Li, Liping, Li, Jinyang, Cheng, Bing, Ma, Xiaoyin, Li, Huirong, Hou, Ling
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361154/
https://ncbi.nlm.nih.gov/pubmed/30651300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.035642
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